Advanced IV infusion centre, Johannesburg

Medically supervised IV infusions in Johannesburg.

A doctor-led IV infusion service in Waverley offering selected NAD+, vitamin C, magnesium and glutathione infusions with medical screening and supervision.

In short

MLI offers medically supervised intravenous therapy at the Centre of Advanced Medicine, including selected NAD+, vitamin C, magnesium and glutathione infusions. These infusions are not interchangeable and they do not have the same level of evidence. Magnesium and vitamin C have established medical uses in specific contexts; intravenous NAD+ and glutathione are more commonly used in wellness settings but have limited evidence for broad longevity or wellness outcomes. Every infusion is screened for indication, contraindications and relevant medical risk.

Medically reviewed by Dr Arnav Kapur, MBBCh Cum Laude

The approach

Understand first. Then treat.

The intravenous route changes pharmacology and bypasses normal gastrointestinal absorption, but that does not automatically make a treatment better or more effective. The reason for using an IV should be clearer than 'wellness'.

Our infusion centre is built around clinician screening, formulation-specific risk review and honest discussion of what is established, what is emerging and what is simply not supported well enough to claim.

Infusions available

  • NAD+ infusions
  • Vitamin C infusions
  • Magnesium infusions
  • Glutathione infusions
  • Selected micronutrient or supportive infusions where clinically appropriate
  • Medical history and medication review before treatment
  • Relevant renal function and laboratory review
  • Infusion-specific contraindication screening
  • G6PD screening where relevant for higher-dose vitamin C protocols
  • Clinical monitoring during infusion

NAD+: biologically interesting, clinically unsettled

NAD+ is central to cellular energy metabolism and redox biology, which is why it has attracted interest in longevity medicine. A 2026 systematic review found biological activity for NAD-related interventions but no eligible clinical outcomes trials of intravenous NAD+ itself for anti-ageing or wellness indications. At MLI, IV NAD+ is therefore presented as an emerging supportive therapy, not a proven treatment for fatigue, cognition, mitochondrial dysfunction or lifespan extension.

Vitamin C: dose and indication matter

Intravenous vitamin C achieves much higher plasma concentrations than oral vitamin C, but the clinical meaning depends on dose and indication. It should not be marketed as an immune booster, cancer cure or universal wellness treatment. Higher-dose protocols require careful medical review, including renal history and relevant contraindications; G6PD screening may be appropriate before high-dose use.

Magnesium: established medicine used selectively

Intravenous magnesium has well-established medical uses, including treatment of severe deficiency and several acute clinical indications. In an outpatient infusion setting, it is used only where the clinical context supports intravenous replacement or treatment rather than simply because magnesium is an important nutrient.

Glutathione: no detox or skin-lightening claims

Glutathione is an endogenous antioxidant, but evidence for routine intravenous use for wellness, anti-ageing, detoxification or cosmetic skin lightening is limited. Published reviews have raised efficacy and safety concerns around IV glutathione for cosmetic use. We do not market it as a detoxification or skin-lightening treatment, and any use follows individual clinical discussion.

Common questions

Answers before you book.

Do IV vitamins work better than oral supplements?

Not automatically. Intravenous delivery can produce higher circulating concentrations and is useful when the IV route itself is clinically indicated, but many vitamins and minerals are effectively replaced orally. The route should be chosen according to indication rather than assumed to be superior.

Is NAD+ proven to improve energy or longevity?

No. NAD+ biology is important, but current human evidence does not establish that intravenous NAD+ improves longevity, cognition, energy or other wellness outcomes. It is offered as an emerging therapy with that limitation made clear.

Do I need blood tests before an infusion?

Not for every low-risk infusion, but laboratory testing may be appropriate depending on the formulation, dose, renal function, medical history and medications. Higher-dose vitamin C protocols may require additional safety screening such as G6PD testing.

Can I book an IV infusion without seeing a doctor?

The infusion service requires appropriate clinical screening. The level of assessment depends on the infusion and your medical history; some patients may need a consultation or bloodwork before treatment.

IV therapies shown on this page are not equivalent in evidence or indication. Availability and suitability depend on individual assessment, product availability and relevant regulatory requirements. Emerging therapies do not replace established medical treatment.

Ready to start properly?

Centre of Advanced Medicine · 13 Scott Street, Waverley, Johannesburg

Monday to Friday, 07:40 to 17:00
011 440 8721